Description
Flora 1000 – Solution
Florfenicol and Colistin
Composition:
Each 100ml Contains
Florfenicol – 10gm
Colistin Sulfate – 2.5gm
Description:
Florfenicol is a synthetic broad-spectrum antibiotic that is effective against most Gram-positive and Gram-negative bacteria isolated from domestic animals. Florfenicol, a fluorinated derivative of chloramphenicol, acts by inhibiting protein synthesis at the ribosomal level and is bacteriostatic.
Florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, and also has activity against some chloramphenicol-resistant strains of bacteria.
Colistin belongs to the polymyxins group of antibiotic with bactericidal action especially against Gram-negative bacteria like E. coli, Haemophilus and Salmonella spp. It is absorbed poorly after oral administration and serum concentrations are generally undetectable in target species. Orally administered colistin is eliminated almost totally in faeces.
Indications:
Flora 1000 – Solution is indicated for preventive and therapeutic treatment of gastrointestinal and respiratory tract infections, caused by florfenicol sensitive micro-organisms such as Actinobaccillus spp. Pasteurella spp. Salmonella spp. and Streptococcus spp. in swine and poultry. The presence of the disease in the herd should be established before preventive treatment. Medication should be initiated promptly when respiratory disease is diagnosed.
Contra indications:
Not to be used in boars intended for breeding purposes, or in animals producing eggs or milk for human consumption.
Do not administer in cases of previous hypersensitivity to florfenicol.
The use of Flora 1000 Solution during pregnancy and lactation is not recommended.
The product should not be used or stored in galvanized metal watering systems or containers.
Side effects:
A decrease in food and water consumption and transient softening of the faeces or diarrhoea may occur during the treatment period. The treated animals recover quickly and completely upon termination of treatment. In swine, commonly observed adverse effects are diarrhoea, peri-anal and rectal erythema/ oedema and prolapse of the rectum. These effects are transient.
Dosage:
For oral administration. The appropriate final dosage should be based on the daily water consumption.
Poultry:
1 litre per 1000 – 2000 litres of drinking water (100 ppm; 10 mg/kg body weight) for 3 days.
Withdrawal times:
– For meat:
Swine : 21 days.
Poultry : 7 days.
Packaging:
Bottle of 1000 ml
Bottle of 500 ml
