Noxy Flor Water Soluble Powder

Noxy Flor – Water Soluble Powder
Neomycin, Florfenicol & Oxytetracycline

Composition:
Each gm contains
Neomycin Sulfate – 150mg
Florfenicol – 100mg
Oxytetracycline HCl – 300mg

Description:
Neomycin is a broad-spectrum bactericidal aminoglycosidic antibiotic with particular activity against certain members of the Enterobacteriaceae e.g. Escherichia coli. Its mode of action is at the ribosomal level. When administered orally, only a fraction (<5%) is absorbed systemically, the remainder remains as the active compound in the gastro-intestinal tract of the animal. Neomycin is not inactivated by enzymes or food. These pharmacological properties lead to neomycin being an efficacious antibiotic in the prevention and treatment of enteric infections caused by bacteria sensitive to neomycin.

Florfenicol is a synthetic broad-spectrum antibiotic that is effective against most Gram-positive and Gram-negative bacteria isolated from domestic animals. Florfenicol, a fluorinated derivative of chloramphenicol, acts by inhibiting protein synthesis at the ribosomal level and is bacteriostatic.
Florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, and also has activity against some chloramphenicol-resistant strains of bacteria.

Oxytetracycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. The mode of action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine and to a lesser degree in bile and in lactating animals in milk.

Indications:
Noxy Flor WSP Gastrointestinal and respiratory infections caused by oxytetracycline, Neomycin & Florfenicol sensitive bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. in calves, goats & poultry.

Contra indications:
Hypersensitivity to neomycin, tetracyclines & Florfenicol
Administration to animals with a seriously impaired renal function.
Administration to animals with an active microbial digestion.
Administration to poultry producing eggs for human consumption.

Side effects:
Discoloration of teeth in young animals.
Hypersensitivity reactions may occur.
Neomycin’s typical toxic effects (nephrotoxicity, deafness, neuromuscular blockade) are generally not produced when it is administered orally. No additional side effects are to be expected when the prescribed dosage regimen is followed correctly.

Dosage:
For oral administration:
Calves, goats and sheep:
Twice daily 1 g per 50 – 100 kg body weight for 3 – 5 days.

Poultry:
1g per 2 -4 litres of drinking water for 3 – 5 days.

Withdrawal times:
– For meat:
Calves, goats, sheep: 21 days.
Poultry: 7 days.

Packaging:
Can of 1000 g
Can of 500 g

Special Note:
Mix Noxy Flor WSP daily with fresh water.
Not intended for hens producing eggs for human consumption.
In severe cases curative treatment may be followed by preventive treatment.

Menu