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DIV E Col Water Soluble Powder


DIV E Col – Water Soluble Powder
Colistin and Enrofloxacin – Oral Liquid

Each 100 g Contains:
Enrofloxacin – 20gm
Colistin Sulfate – 45MIU

The combination of enrofloxacin and colistin acts synergistically. Enrofloxacin is a synthetic, broad spectrum antibacterial, member of fluoroquinoline group of antibiotics.

Enrofloxacin acts against Gram-negative, Gram-positive bacteria & mycoplasmas. It’s duly when administered orally and abruptly excreted in bile and urine, frequently as suchor as the metabolite ciprofloxacin.

Colistin belongs to the polymyxins group of antibiotic with bactericidal action especially against Gram-negative bacteria like E. coli, Haemophilus and Salmonella spp. It is absorbed poorly after oral administration and serum concentrations are generally undetectable in target species. Orally administered colistin is eliminated almost totally in faeces.

DIV E Col – WSP is indicated for gastrointestinal, respiratory and urinary tract infections caused by colistin and enrofloxacin sensitive micro-organisms like Campylobacter, E. coli, Haemophilus, Mycoplasma, Pasteurella and Salmonella spp. in poultry and swine.

Contra indications:
Should not be administered in cases of
– hypersensitivity to colistin and/or enrofloxacin or to any of the excipients.
– seriously impaired renal and/or hepatic functions.
– Cases of resistance against quinolones and/or colistin.
– poultry producing eggs for human consumption.

Side effects:
All members of the quinolone family of antibiotics have the ability to cause articular lesions in young animals.
Digestive alterations may appear, such as intestinal dysbiosis, accumulation of gases, mild diarrhoea or vomiting.
Side-effects for quinolones like rash and central nervous system disturbance may occur.
During a period of rapid growth, enrofloxacin may affect joint cartilage.

For oral administration:

1 ml per 4 litres of drinking water for 3 – 5 days.

Withdrawal times
– For meat and offal: 9 days.

Bottle of 1000 ml.
Bottle of 500 ml

Special Note:
Only sufficient medicated drinking water should be prepared to cover daily requirements. Medicated drinking water should be replaced every 24 hours.